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醋甲唑胺
Methazolamide
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3109256 | 50 MG | 1740 |
产品别名
554-57-4
醋甲唑胺
Methazolamide
5-Acetylimino-4-methyl-·2-1,3,4-thiadiazoline-2-sulfonamide
N-[5-(Aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
L 584601
N-(4-Methyl-2-sulfamoyl-Δ2-1,3,4-thiadiazolin-5-ylidene) acetamide
N-(4-甲基-2-氨基磺酰基-Δ2-1,3,4-噻二唑-5-亚基)乙酰胺
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C5H8N4O3S2 |
| Molecular weight | 236.27 |
| EC number【EC 号】 | 209-066-7 |
| MDL number | MFCD00083416 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825590 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Methazolamide has a plasma half-life of 14 hours in humans. Methazolamide has relatively good lipid solubility and low plasma protein binding ability. Thus, it diffuses into tissues and fluids much more readily than acetazolamide, another carbonic anhydrase inhibitor. Methazolamide has less side effects than acetazolamide. Methazolamide is a cell-permeable and potent carbonic anhydrase (CA) inhibitor that is used in the treatment of glaucoma. Methazolamide is an insulin sensitizer that reduces hepatic glucose generation in animal models. |
| Other Notes【其他说明】 | Light sensitive |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | protect from light |
| color【颜色】 | white to beige |
| mp | 208 ℃ (dec.) (lit.) |
| solubility【溶解性】 | DMSO: 20 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CN1N=C(S\C1=N\C(C)=O)S(N)(=O)=O |
| InChI | 1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)/b7-4+ |
| InChI key | FLOSMHQXBMRNHR-QPJJXVBHSA-N |
| Gene Information | human ... CA1(759), CA2(760), CA4(762), CA7(766) |
| packaging【包装】 | 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07,GHS08 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 + H312 + H332 - H351 |
| Precautionary Statements | P201 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
