Anti-Actin (α-Sarcomeric) antibody, Mouse monoclonal antibody produced in mouse

NA.41

Monoclonal Anti-Actin (α-Sarcomeric) (mouse IgM isotype) is derived from the hybridoma 5C5 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with purified rabbit striated muscle. Actin is one of the major cytoskeletal proteins in eukaryotic cells.

purified rabbit striated muscle

Monoclonal Anti-Actin (α-Sarcomeric) antibody produced in mouse has been used in:

• western blotting
• enzyme linked immunosorbent assay (ELISA)
• immunohistochemistry

Actin plays an essential role in various cellular processes including cell migration, cytokinesis, vesicle transport, and contractile force generation. Pathological conditions influenced by genetic and/or environmental factors causes variations in the sarcomeric actin filaments. These variations in the actin filaments leads to the development of congenital myopathy, a genetic muscle disorder.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

mouse

purified from hybridoma cell culture

primary antibodies

5C5, monoclonal

buffered aqueous solution

antigen ~42 kDa

human, carp, rabbit, frog, rat, bovine, snake, sheep, guinea pig

~1.0 mg/mL

immunoblotting: suitable
immunohistochemistry: 1-2 μg/mL using formalin-fixed, paraffin embedded human tongue
indirect ELISA: suitable

IgM

dry ice

−20℃

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

12 - Non Combustible Liquids