广州伟伯科技有限公司
您的位置:首页 > 产品中心 > Monoclonal Anti-Cathepsin L antibody produced in mouse
产品搜索:

Monoclonal Anti-Cathepsin L antibody produced in mouse

产品编号:3142178
规格:clone 33/2, ascites fluid
包装规格:0.5 ML
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
31421780.5 ML7200
产品别名

Monoclonal Anti-Cathepsin L antibody produced in mouse

Anti-CATL

Anti-MEP

Anti-CTSL

基本信息
MDL number
MFCD01321805
NACRES
NA.41
General description【一般描述】
Cathepsin L is a cysteine protease and is secreted by numerous transformed cells in its inactive pre-form. It is ubiquitously expressed and is localized in nucleus. Cathepsin L have substrate interacting region located in L and R domain loops.
Specificity【特异性】
Reacts specifically with native and denatured forms of human cathepsin L and procathepsin L. Recognizes an epitope within amino acid residues GYGFEST (265-271 in procathepsin L and 169-175 in the mature cathepsin L molecule). The antibody may be used for the suppression of the malignant growth of myeloma cells. Cross-reactivity is observed with rat cathepsin L (strong), mouse procathepsin L (weak) and mink cathepsin and procathepsin L. Does not cross-react with human cathepsin types B, D, H and S, procathepsins B and D, rat cathepsin B, and mouse procathepsins B and D.
Immunogen【免疫原】
procathepsin L isolated from the human lung cancer cell line EPLC 32M1.
Biochem/physiol Actions【生化/生理作用】
Cathepsin L expression is correlated with the metastatic potential of transformed cells. Cathepsin L is capable of degrading protein constituents of the extracellular matrix, this enzyme is thought to play a crucial role in tumor progression, metastasis and other disorders where the destruction of the matrix is the major cause of disease.
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
ascites fluid
antibody product type
primary antibodies
clone【克隆】
33/2, monoclonal
mol wt【分子量】
antigen (human cathepsin L) 25 kDa
antigen (human procathepsin L) 42 kDa
contains【包含】
15 mM sodium azide
species reactivity
human, mink, rat, mouse
technique(s)
immunohistochemistry (frozen sections): suitable
indirect ELISA: suitable
microarray: suitable
western blot: 1:200 using whole cell extract of a cultured mink lung cell line
isotype【同位素/亚型】
IgG1
UniProt accession no.【UniProt登记号】
P07711
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... CTSL1(1514)
mouse ... Ctsl(13039)
rat ... Ctsl1(25697)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
广州伟伯科技有限公司 版权所有 CopyRight ©2006-2024, All Rights Reserved
工信部备案号:粤ICP备08114744号   Page Run Time: 0.0079