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Monoclonal Anti-Na+/Ca2+ Exchanger antibody produced in mouse

产品编号:3148912
规格:clone C2C12
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3148912100 μL9620
基本信息
MDL number
MFCD01865491
NACRES
NA.41
General description【一般描述】
Na+/Ca2+ exchanger is also known as solute carrier family 8 member A1 (SLC8A1) and is present in the plasma membrane. It is predicted to have nine transmembrane segments and the gene encoding SLC8A1 has three promoters.
Specificity【特异性】
The antibody reacts specifically with Na+/Ca2+ exchanger in kidney and cardiac tissues. By immunohistology, staining of the plasma membrane and intense staining of the cardiac T-tubular membrane is observed. The antibody is not recommended for immunoblotting of rat tissues.
Immunogen【免疫原】
dog cardiac Na+/Ca2+ exchanger. The epitope is in the region of amino acids 371-525, which is on the intracellular side of the plasma membrane.
Biochem/physiol Actions【生化/生理作用】
Na+/Ca2+ exchanger (SLC8A1, solute carrier family 8 member A1) is involved in Ca2+ homeostasis. Depending on physiological conditions prevailing in the cell, it can either pump out Na+ or Ca2+.
Physical form【外形】
Solution in phosphate buffered saline, 1 mg/ml BSA containing 0.05% sodium azide.
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody product type
primary antibodies
clone【克隆】
C2C12, monoclonal
form【形式】
liquid
mol wt【分子量】
antigen 120 kDa (mature exchanger)
antigen 160 kDa (non-reduced)
antigen 70 kDa (proteolytic fragment)
species reactivity
canine, rat, guinea pig, human, rabbit
technique(s)
immunohistochemistry (frozen sections): 1:200
immunoprecipitation (IP): suitable
western blot: 1:1,000
isotype【同位素/亚型】
IgM
UniProt accession no.【UniProt登记号】
P32418
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... SLC8A1(6546)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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