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Monoclonal Anti-Plakoglobin (Catenin γ) antibody produced in mouse
| 产品编号： | 3150372 |
| 规格： | clone 15F11, ascites fluid, buffered aqueous solution |
| 包装规格： | 100 μL，0.2 ML |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| MDL number | MFCD00164716 |
| NACRES | NA.41 |
| General description【一般描述】 | Plakoglobin is a desmosomal protein that regulates developmental signalling in vertebrates. Tyrosine phosphorylation of plakoglobin has been linked to adenocarcinomas . Plakoglobin may function as a tumor suppressor in ovarian and breast cancers . |
| Specificity【特异性】 | The antibody recognizes the plakoglobin (catenin-γ) molecule (85 kDa and possibly a slightly lower band) by immunoblotting. It does not cross-react with β-catenin. The antibody reacts with plakoglobin in bovines, humans and dogs, but does not react with β catenin. |
| Immunogen【免疫原】 | recombinant chicken plakoglobin. |
| Application【应用】 | Monoclonal anti-plakoglobin (catenin γ) antibody is suitable for use in immunocytochemistry (using MDCK cells), immunoprecipitation, and in immunoblotting . The antibody may also be used for immunohistochemistry (frozen sections), microarray, western blot (1:500, using cultured MDBK cells) and indirect immunofluorescence (1:1000, using cultured MDBK cells). |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | ascites fluid |
| antibody product type | primary antibodies |
| clone【克隆】 | 15F11, monoclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 85 kDa |
| contains【包含】 | 15 mM sodium azide |
| species reactivity | canine, bovine, human |
| technique(s) | immunocytochemistry: suitable using cultured cells immunohistochemistry (frozen sections): suitable immunoprecipitation (IP): suitable indirect immunofluorescence: 1:1,000 using cultured MDBK cells microarray: suitable western blot: 1:2,000 using cultured MDBK cells |
| isotype【同位素/亚型】 | IgG1 |
| UniProt accession no.【UniProt登记号】 | P14923 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... JUP(3728) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
