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Monoclonal Anti-PTK2B antibody produced in mouse
产品别名
Monoclonal Anti-PTK2B antibody produced in mouse
CAKB
FRNK
PKB
PTK
FAK2
基本信息
NACRES | NA.41 |
General description【一般描述】 | Protein tyrosine kinase 2 β (PTK2B) is a member of the focal adhesion kinase family which is expressed in the brain. The gene encoding it is localized on human chromosome 8. |
Immunogen【免疫原】 | Purified recombinant fragment of PYK2 (aa815-997) expressed in E.coli. Mouse monoclonal antibody raised against PYK2 |
Biochem/physiol Actions【生化/生理作用】 | Protein tyrosine kinase 2 β (PTK2B) takes part in the β2-mediated signaling pathway and activates mitogen activated protein kinase pathway. The protein has been shown to be upregulated in many tumors. PTK2B also has a role in cell proliferation and migration. It regulates ion channels which are induced by calcium. |
Physical form【外形】 | Ascitic fluid containing 0.03% sodium azide. |
产品性质
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | ascites fluid |
antibody product type | primary antibodies |
clone【克隆】 | 5E2D5, monoclonal |
mol wt【分子量】 | 115.8 kDa |
species reactivity | human |
technique(s) | direct ELISA: 1:10,000 immunohistochemistry: 1:200-1:1,000 western blot: 1:500-1:2,000 |
isotype【同位素/亚型】 | IgG2a |
NCBI accession no.【NCBI登记号】 | NM_173174 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... PYK2(2185) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |