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Monoclonal Anti-RASA3, (C-terminal) antibody produced in mouse
产品别名
Monoclonal Anti-RASA3, (C-terminal) antibody produced in mouse
MGC46517
MGC47588
GAP1IP4BP
GAPIII
基本信息
NACRES | NA.41 |
General description【一般描述】 | The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane. (provided by RefSeq) |
Immunogen【免疫原】 | RASA3 (AAH47242, 725 a.a. ~ 834 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence DGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEYSTFVIDDPQETYKTLKQVIAGVGALEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQNYIRQQSETSTHSI |
Physical form【外形】 | Clear solution |
产品性质
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | ascites fluid |
antibody product type | primary antibodies |
clone【克隆】 | 1F11, monoclonal |
mol wt【分子量】 | antigen ~38.1 kDa |
species reactivity | human |
technique(s) | indirect ELISA: suitable western blot: 1:500-1:1000 |
isotype【同位素/亚型】 | IgG2aκ |
NCBI accession no.【NCBI登记号】 | BC047242 |
UniProt accession no.【UniProt登记号】 | Q14644 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... RASA3(22821) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 1 |