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Monoclonal Anti-SNX6 antibody produced in mouse
| 产品编号： | 3152500 |
| 规格： | clone SNX6-76, ascites fluid, buffered aqueous solution |
| 包装规格： | 200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-SNX6 antibody produced in mouse
Anti-Tumor necrosis factor receptor-associated factor 4(TRAF4)-associated factor 2
Anti-Sorting Nexin 6
Anti-TFAF2
Anti-MSTP010
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Monoclonal Anti-SNX6 (mouse IgA isotype) is derived from the hybridoma SNX6-76 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. SNX6 (sorting nexin 6) is a BACE1 (Β-site APP cleaving enzyme-1)-associated protein and a constituent of retromer. It belongs to the sorting nexin (SNX) family that has a PX (Phox homology) domain at its amino terminus and a BAR (Bin/amphiphysin/Rvc) domain at its carboxyl region. It is located on chromosome 14q13. |
| Application【应用】 | Monoclonal Anti-SNX6 antibody produced in mouse has been used in immunoblotting and ELISA. |
| Biochem/physiol Actions【生化/生理作用】 | SNX6 (sorting nexin 6) helps in retrograde trafficking of the cation-independent mannose-6-phosphate receptor (CI-MPR) and sortilin. Interaction of SNX6 with breast cancer metastasis suppressor-1 induces transcriptional repression. It helps in the synthesis of lamin A and its transportation to the nuclear envelope . |
| Physical form【外形】 | 0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。 |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | ascites fluid |
| antibody product type | primary antibodies |
| clone【克隆】 | SNX6-76, monoclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~47 kDa |
| species reactivity | rat, human, bovine, mouse |
| packaging【包装】 | antibody small pack of 25 μL |
| technique(s) | indirect ELISA: suitable western blot: 1:2,500-1:5,000 using total extracts of A549 cells |
| isotype【同位素/亚型】 | IgA |
| UniProt accession no.【UniProt登记号】 | Q9UNH7 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SNX6(58533) mouse ... Snx6(72183) rat ... Snx6(362738) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
