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Monoclonal Anti-Sonic Hedgehog (N-terminal) antibody produced in rat
| 产品编号： | 3152522 |
| 规格： | clone 171018, purified immunoglobulin, lyophilized powder |
| 包装规格： | 500 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-Sonic Hedgehog (N-terminal) antibody produced in rat
Anti-Shh
基本信息
| MDL number | MFCD06798717 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | purified, E. coli-derived, recombinant mouse sonic hedgehog N-terminal peptide (amino acids 25-198). |
| Biochem/physiol Actions【生化/生理作用】 | Shh protein is secreted by Purkinje cells in the cerebellum with both autocrine and paracrine functions. The Shh signaling is mediated by the interaction of Shh with transmembrane proteins, Patched and Smoothened. The Shh pathway cross-talks Notch and Wnt pathways and acts via downstream targets such as cyclins, gamma catenin, myc and other transcription factors. The Hh family members have multiple roles as morphogens, cell survival factors, setting anterior-posterior axis and digit formation during development of limb and axon guidance factors during the development of brain and nervous system. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | rat |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 171018, monoclonal |
| form【形式】 | lyophilized powder |
| species reactivity | mouse, human |
| technique(s) | capture ELISA: suitable immunohistochemistry (frozen sections): 25 μg/mL using mouse embryo neutralization: suitable western blot: 1-2 μg/test |
| isotype【同位素/亚型】 | IgG2a |
| UniProt accession no.【UniProt登记号】 | Q15465 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SHH(6469) mouse ... Shh(20423) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
