Monoclonal Anti-Sonic Hedgehog Peptide (C-terminal) antibody produced in rat

NA.41

purified, E. coli-derived recombinant mouse 6× histidine-tagged sonic hedgehog C-terminal peptide (aa 199-437).

Shh protein is secreted by Purkinje cells in the cerebellum with both autocrine and paracrine functions. The Shh signaling is mediated by the interaction of Shh with transmembrane proteins, Patched and Smoothened. The Shh pathway cross-talks Notch and Wnt pathways and acts via downstream targets such as cyclins, gamma catenin, myc and other transcription factors. The Hh family members have multiple roles as morphogens, cell survival factors, setting anterior-posterior axis and digit formation during development of limb, and axon guidance factors during the development of brain and nervous system.

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

rat

unconjugated

purified immunoglobulin

primary antibodies

55626, monoclonal

lyophilized powder

mouse

western blot: 1-2 μg/mL

IgG2a

Q62226

−20℃

mouse ... Shh(20423)

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

13 - Non Combustible Solids

WGK 1

Eyeshields, Gloves, type N95 (US)