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Monoclonal Anti-Sonic Hedgehog peptide (N-terminal) antibody produced in rat
| 产品编号： | 3152524 |
| 规格： | clone 171001, purified immunoglobulin, lyophilized powder |
| 包装规格： | 500 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-Sonic Hedgehog peptide (N-terminal) antibody produced in rat
Anti-DSH
Anti-HHG1
Anti-Shh
Anti-Hx
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | purified, E. coli-derived recombinant mouse 6× histidine-tagged sonic hedgehog N-terminal peptide (aa 25-198). |
| Biochem/physiol Actions【生化/生理作用】 | Shh protein is secreted by Purkinje cells in the cerebellum with both autocrine and paracrine functions. The Shh signaling is mediated by the interaction of Shh with transmembrane proteins, Patched and Smoothened. The Shh pathway cross-talks Notch and Wnt pathways and acts via downstream targets such as cyclins, gamma catenin, myc and other transcription factors. The Hh family members have multiple roles such as morphogens, cell survival factors, setting anterior-posterior axis and digit formation during the development of brain and nervous system. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | rat |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 171001, monoclonal |
| form【形式】 | lyophilized powder |
| species reactivity | mouse, human |
| technique(s) | western blot: 1-2 μg/mL |
| isotype【同位素/亚型】 | IgG2a |
| UniProt accession no.【UniProt登记号】 | Q15465 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SHH(6469) mouse ... Shh(20423) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
