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Monoclonal Anti-Sox2 antibody produced in mouse

产品编号:3152551
规格:clone 10F10, ascites fluid
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3152551100 μL5040
产品别名

Monoclonal Anti-Sox2 antibody produced in mouse

ysb

Sox2

Sox-2

lcc

基本信息
NACRES
NA.41
General description【一般描述】
SOX2 (sex-determining region Y-box 2) is a transcription factor consisting of 317 amino acids. It has an HMG (high mobility group box) domain and is a critical transcription regulator of normal stem cell. It is located on human chromosome 3q26.3.
Immunogen【免疫原】
Purified recombinant fragment of human SOX2 expressed in E.coli.
Mouse monoclonal antibody raised against SOX2
Application【应用】
Monoclonal Anti-SOX2 antibody has been used as a core pluripotency factor to regulate stem cell pluripotency.
Biochem/physiol Actions【生化/生理作用】
SOX2 (sex-determining region Y-box 2) down-regulation reduces the stem cell count, that affects breast cancer cells in initiating tumor progression. It participates in chemoresistance and regular lung cancer therapies. In mouse, SOX2 plays an important role in branching morphogenesis and regulating lung epithelial cell differentiation.
Physical form【外形】
Ascitic fluid containing 0.03% sodium azide.
产品性质
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
ascites fluid
antibody product type
primary antibodies
clone【克隆】
10F10, monoclonal
mol wt【分子量】
34 kDa
species reactivity
human
technique(s)
direct ELISA: 1:10,000
immunohistochemistry: 1:200-1:1,000
indirect immunofluorescence: 1:200-1:1,000
western blot: 1:500-1:2,000
isotype【同位素/亚型】
IgG1
UniProt accession no.【UniProt登记号】
P48431
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... SOX2(20674)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
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