Anti-TGN46 antibody, Mouse monoclonal

MFCD09265378

Monoclonal Anti-TGN46 (mouse IgG1 isotype) is derived from the hybridoma TGN46-52 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to a fragment of human TGN46 conjugated to KLH. Trans-Golgi network protein 46-kDa (TGN46), It is a heavily glycosylated protein, containing a signal peptide, a lumenal domain, a membrane-spanning domain and a cytoplasmic domain. The membrane spanning region and the cytoplasmic tail contain the retention and retrieval signals for localization in the TGN.

Monoclonal Anti-TGN46 antibody produced in mouse has been used in immunoblotting and immunoprecipitation.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Trans-Golgi network protein, 46-kDa (TGN46) is involved in regulating membrane traffic to and from the TGN. It cycles constitutively between the TGN and the plasma membrane, returning via endosomes.

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

mouse

unconjugated

purified from hybridoma cell culture

primary antibodies

TGN46-52, monoclonal

buffered aqueous solution

antigen 80-100 kDa

human

~1 mg/mL

immunoprecipitation (IP): suitable
western blot: 1-2 μg/mL using whole extracts of HEK-293T cells over-expressing human TGN46

IgG1

dry ice

−20℃

human ... TGN46(10618)

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12 - Non Combustible Liquids

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