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Monoclonal Anti-UBR2, (N-terminal) antibody produced in mouse
产品别名
Monoclonal Anti-UBR2, (N-terminal) antibody produced in mouse
C6orf133
KIAA0349
bA49A4.1
dJ392M17.3
dJ242G1.1
RP3-392M17.3
MGC71112
DKFZp686C08114
产品性质
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | ascites fluid |
| antibody product type | primary antibodies |
| clone【克隆】 | 4G4, monoclonal |
| mol wt【分子量】 | antigen ~37.11 kDa |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG2aκ |
| NCBI accession no.【NCBI登记号】 | NM_015255 |
| UniProt accession no.【UniProt登记号】 | Q8IWV8 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... UBR2(23304) |
基本信息
| General description【一般描述】 | Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate′s destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM |
| Immunogen【免疫原】 | UBR2 (NP_056070, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCG |
| Physical form【外形】 | Clear solution |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
