Anti-PP2A, C subunit antibody, Mouse monoclonal

NA.44

PP2A is a serine/threonine phosphatase that downregulates the MAP kinase pathway and subsequently modulates mitogenic signaling. This phosphatase also mediates localization of Sgo1 at centromeres, Ras-1 activation, and chromosome segregation. The catalytic subunit of PP2A (PP2Ac) regulates the signaling pathway for glucose-stiμLated insulin secretion .

Monoclonal Anti-PP2Ac is specific for the α and β isoforms of PP2Ac in humans, rats and mice. The antibody has not been tested in other species for cross-reactivity.

MonoclonalAnti-PP2A, C subunit antibody produced in mouse has been used in immunoblotting and immunoprecipitation.

Protein phosphatase 2A (PP2A) is implicated in the negative control of cell growth and division. PP2Ac undergoes two post-translational modifications, phosphorylation and methylation, which are involved in the regulation of the enzyme activity.

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

200

mouse

unconjugated

purified from hybridoma cell culture

primary antibodies

7A6, monoclonal

buffered aqueous solution

antigen 36 kDa

human, mouse, rat

~1.0 mg/mL

immunoprecipitation (IP): suitable
western blot: 1-2 μg/mL using whole extracts of mouse 3T3, rat Rat2 or human A431 cells.

IgG1

P67775

dry ice

−20℃

human ... PPP2CA(5515)
mouse ... Ppp2ca(19052)
rat ... Ppp2ca(24672)

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12 - Non Combustible Liquids