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MoTP
产品别名
57055-82-0
MoTP
4-(4-Morpholinobutylthio)phenol
33N14
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C14H21NO2S |
| Molecular weight | 267.39 |
| MDL number | MFCD00642470 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825117 |
| NACRES | NA.77 |
| Application【应用】 | MoTP may be used in cell signaling and differentiation studies. |
| Biochem/physiol Actions【生化/生理作用】 | MoTP (also known as 33N14) reversibly blocks the specification of neural crest cells into melanocytes in zebrafish studies. Differentiation of neural crest cell-derived melanoblasts proceeds to late developmental stages, but they fail to reach the terminal stage of melanin production and die. Melanocytotoxicity is dependent on tyrosinase activity which convert it into a toxic form. MoTP specifically ablates only cells that express tyrosinase at high levels, which in the embryo are limited to melanoblasts and newly formed melanocytes. MoTP should be a useful tool for elucidating melanocyte stem cell regeneration, recruitment, and maintenance. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to tan |
| solubility【溶解性】 | DMSO: ≥80 mg/mL |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | Oc1ccc(SCCCCN2CCOCC2)cc1 |
| InChI | 1S/C14H21NO2S/c16-13-3-5-14(6-4-13)18-12-2-1-7-15-8-10-17-11-9-15/h3-6,16H,1-2,7-12H2 |
| InChI key | YHKNLUTUXZDOQI-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
