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N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide
产品别名
N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide
Ac-IETD-pNA
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H38N6O12 |
| Molecular weight | 638.62 |
| MDL number | MFCD01318840 |
| PubChem Substance ID【PubChem化学物质编号】 | 329771065 |
| NACRES | NA.32 |
| Amino Acid Sequence | NAc-Ile-Glu-Thr-Asp-pNA |
| Application【应用】 | Chromogenic substrate for caspase 8 and granzyme B. |
| Biochem/physiol Actions【生化/生理作用】 | IETD is the sequence of amino acid residues 172-175 of procaspase 3, which is cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3. |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ≥95% |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc(cc1)[N+]([O-])=O |
| InChI | 1S/C27H38N6O12/c1-5-13(2)22(28-15(4)35)26(42)30-18(10-11-20(36)37)24(40)32-23(14(3)34)27(43)31-19(12-21(38)39)25(41)29-16-6-8-17(9-7-16)33(44)45/h6-9,13-14,18-19,22-23,34H,5,10-12H2,1-4H3,(H,28,35)(H,29,41)(H,30,42)(H,31,43)(H,32,40)(H,36,37)(H,38,39)/t13-,14+,18-,19-,22-,23-/m0/s1 |
| InChI key | FHURKTIGZAIQGR-BQCLNCLCSA-N |
| Gene Information | human ... CARD8(22900), CASP8(841), CASP8AP2(9994), CFLAR(8837), GZMB(3002) mouse ... CFLAR(117279), GZMB(171528) rat ... CASP8(12370), CFLAR(12633), GZMB(14939), RGD1561819(502004), RGD1562700(502007) |
| packaging【包装】 | 5 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
