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n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate
产品别名
n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate
compound 10i
Cytosporone A n-amyl ester
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C22H34O5 |
| Molecular weight | 378.50 |
| MDL number | MFCD18632550 |
| PubChem Substance ID【PubChem化学物质编号】 | 329770645 |
| Biochem/physiol Actions【生化/生理作用】 | n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate is a Nur77 agonist. Nur77 is a steroid orphan receptor that plays a critical role in regulating proliferation, differentiation and apoptosis. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate, a cytosporone B analog, is a stronger activator of Nur77 than it parent compound. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate treatment causes Nur77 migration to mitochondria, which results in mitochondrial Cyt c release into the cytoplasm and mitochondrial AIF redistribution in both the cytoplasm and nucleus. |
| Features and Benefits【特点和优势】 | This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: >65 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CCCCCCCCC(=O)c1c(O)cc(O)cc1CC(=O)OCCCCC |
| InChI | 1S/C22H34O5/c1-3-5-7-8-9-10-12-19(24)22-17(14-18(23)16-20(22)25)15-21(26)27-13-11-6-4-2/h14,16,23,25H,3-13,15H2,1-2H3 |
| InChI key | FCKDHZVFIMRCNM-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
