萘普生 钠

C₁₄H₁₃NaO₃

252.24

247-486-2

MFCD00058507

329823182

NA.24

Naproxen sodium (NS) is a sodium salt of propionic acid derivative and demonstrates analgesic, anti-pyretic, and anti-inflammatory properties. It exhibits efficiency in being used as an indomethacin in the treatment of acute musculoskeletal disorders. It belongs to the group of nonsteroidal anti-inflammatory drugs (NSAIDS) and acts by inhibiting the activity of both the cyclooxygenase enzymes, COX-1 & COX-2 and further blocking the synthesis of certain prostaglandins. It is administered in the treatment of ankylosing spondylitis, osteoarthritis, rheumatoid disorders, acute gout, mild to moderate pain, tendonitis, bursitis, dysmenorrhea, fever, and migraine headache. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Naproxen sodium may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and combined dosage forms by chromatographic and spectrophotometric techniques.

环加氧酶(前列腺素 H 合成酶 1 和 2)抑制剂。

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Values of analytes vary lot to lot.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA7178 in the slot below. This is an example certificate only and may not be the lot that you receive.

300

certified reference material
pharmaceutical secondary standard

current certificate can be downloaded

HPLC: suitable
gas chromatography (GC): suitable

pharmaceutical (small molecule)

neat

traceable to USP 1457403

2-30℃

[Na+].COc1ccc2cc(ccc2c1)[C@H](C)C([O-])=O

1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1

CDBRNDSHEYLDJV-FVGYRXGTSA-M

human ... PTGS1(5742), PTGS2(5743)

GHS07,GHS08

Danger

H302 - H360

P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313

Acute Tox. 4 Oral - Repr. 1A

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK 3