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Nepafenac

产品编号:3172936
规格:≥98% (HPLC)
CAS NO:78281-72-8
包装规格:10 MG,50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
317293610 MG840
317293650 MG3260
产品别名

78281-72-8

Nepafenac

2-Amino-3-benzoyl-benzeneacetamide

AL 6515

AHR 9434

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C15H14N2O2
Molecular weight
254.28
MDL number
MFCD08067732
PubChem Substance ID【PubChem化学物质编号】
329825296
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) that is routinely used in opthamology to control pain following cataract surgery.
Nepafenac, a prodrug of amfenac, is used in the treatment of diabetic retinopathy. It is metabolized to its active form through intraocular enzymatic hydrolysis. Nepafenac has a molecular weight of 254.28 kDa and effectively penetrates through the cornea. Its molecule structure enables nepafenac to possess better permeability. Nepafenac has a low inhibitory effect on cyclooxygenase.
产品性质
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
faintly yellow to dark yellow
solubility【溶解性】
DMSO: ≥5 mg/mL
storage temp.【储存温度】
room temp
SMILES string
NC(=O)Cc1cccc(c1N)C(=O)c2ccccc2
InChI
1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)
InChI key
QEFAQIPZVLVERP-UHFFFAOYSA-N
Gene Information
human ... PTGS1(5742), PTGS2(5743)
packaging【包装】
10, 50 mg in glass bottle
安全信息
Pictograms【象形图】
GHS09
Signal word【警示用语:】
Warning
Hazard Statements
H400
Precautionary Statements
P273
Hazard Classifications【危险分类】
Aquatic Acute 1
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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