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奈韦拉平
Nevirapine
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3173052 | 10 MG | 1110 | |||
| 3173052 | 50 MG | 4110 |
产品别名
129618-40-2
奈韦拉平
Nevirapine
11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one
11-环丙基-5,11-二氢-4-甲基-6H-二吡啶基[3,2-b:2′,3′-e][1,4] 二氮杂- 6-酮
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C15H14N4O |
| Molecular weight | 266.30 |
| MDL number | MFCD00866928 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825155 |
| NACRES | NA.77 |
| Application【应用】 | Nevirapine has been used as non-nucleoside reverse transcriptase inhibitor in in vitro porcine endogenous retrovirus replication, primary hepatocytes and bone marrow dendritic cells (BMDCs). |
| Biochem/physiol Actions【生化/生理作用】 | 奈韦拉平是 HIV 逆转录酶(NNRTI)的变构非核苷抑制剂。奈韦拉平抑制野生型 RT 的 Ki 为 200 nM。 Nevirapine interacts with glycine 190 residue of human immuno deficiency virus (HIV-2) reverse transcriptase. It is an antiretroviral drug which increases bile synthesis and activates electron transport chain. Use of nevirapine leads to liver toxicity and is associated with Nevirapine hypersensitivity syndrome. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to tan |
| solubility【溶解性】 | DMSO: ≥22 mg/mL |
| storage temp.【储存温度】 | room temp |
| SMILES string | CC1=CC=NC2=C1NC(C(C=CC=N3)=C3N2C4CC4)=O |
| InChI | 1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20) |
| InChI key | NQDJXKOVJZTUJA-UHFFFAOYSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 2 |
