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Nodinitib-1
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3175642 | 5 MG | 1340 | |||
| 3175642 | 25 MG | 4930 |
产品别名
799264-47-4
Nodinitib-1
1-[(4-Methylphenyl)sulfonyl]-1H-benzimidazol-2-amine
CID-1088438
ML130
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C14H13N3O2S |
| Molecular weight | 287.34 |
| MDL number | MFCD04322367 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825379 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Nodinitib-1 (ML130) is a selectiove inhibitor of of the nucleotide oligomerization domain (NOD)-1 receptor, which is involved in innate immune response and has been associated with several inflammatory diseases. NOD1 and NOD2 recognize distinct structures derived from bacterial peptidoglycans and directly activate NF-?B pathway, which controls the production of proinflammatory molecules. Nodinitib-1 has 40:1 selectivity for NOD1 over NOD2. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: >10 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | NC1=NC2=C(N1S(C3=CC=C(C)C=C3)(=O)=O)C=CC=C2 |
| InChI | 1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16) |
| InChI key | SRFABRWQVPCPRG-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
