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诺米芬辛 马来酸盐
Nomifensine maleate salt
产品别名
32795-47-4
诺米芬辛 马来酸盐
Nomifensine maleate salt
1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine maleate salt
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H18N2 · C4H4O4 |
| Molecular weight | 354.40 |
| EC number【EC 号】 | 251-223-7 |
| MDL number | MFCD00069320 |
| PubChem Substance ID【PubChem化学物质编号】 | 24277920 |
| NACRES | NA.77 |
| Application【应用】 | Nomifensine maleate salt has been used to study the β-CFT (cocaine analogue) binding using human embryonic kidney 293T cells. |
| Biochem/physiol Actions【生化/生理作用】 | Nomifensine maleate is a selective dopamine uptake inhibitor interacting with the dopamine transporter, at a site different from that of cocaine; antidepressant. Nomifensine serves as an antidepressant and is known to cause frequent hemolytic anemia. The aniline group in this compound results in blood and liver toxicities. |
| Features and Benefits【特点和优势】 | This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| form【形式】 | powder |
| Quality Level【质量水平】 | 200 |
| SMILES string | [H]\C(=C(/[H])C(O)=O)C(O)=O.CN1CC(c2ccccc2)c3cccc(N)c3C1 |
| InChI | 1S/C16H18N2.C4H4O4/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18;5-3(6)1-2-4(7)8/h2-9,14H,10-11,17H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1- |
| InChI key | GEOCVSMCLVIOEV-BTJKTKAUSA-N |
| Gene Information | human ... DBH(1621), SLC6A2(6530), SLC6A3(6531), SLC6A4(6532) |
| packaging【包装】 | 100 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 - H315 - H319 - H335 |
| Precautionary Statements | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
