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Ogerin negative control
产品别名
1125453-08-8
Ogerin negative control
3-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]-benzenemethanol
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H17N5O |
| Molecular weight | 307.35 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825912 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Ogerin negative control is a structurally similar analog of ogerin (catalog no. SML1482). Ogerin is a selective positive allosteric modulator of an orphan GPCR, GPR68, also known as Ovarian cancer G-protein coupled receptor 1 (OGR1). GPR68 is one of the proton or pH-sensing GPCRs that sense extracellular H(+). Ogerin potently potentiated proton-mediated GPR68-Gs signaling. The meta-analog is inactive and serves as a negative control. |
| Recommended products【推荐产品】 | The positive allosteric modulator, ogerin, is available from Sigma. To learn more about and purchase ogerin, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 20 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | NC1=NC(C2=CC(CO)=CC=C2)=NC(NCC3=CC=CC=C3)=N1 |
| InChI | 1S/C17H17N5O/c18-16-20-15(14-8-4-7-13(9-14)11-23)21-17(22-16)19-10-12-5-2-1-3-6-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22) |
| InChI key | RVKAHYFWSKSSQQ-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
