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PEG4-SPDP (PEGylated, long-chain SPDP crosslinker)
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C23 H33 N3 O9 S2 |
| Molecular weight | 559.65 |
| General description【一般描述】 | SPDP-type reagents have an amine-reactive N-hydroxysuccinimide (NHS) ester at one end and a suflhydryl-reactive 2-pyridyldithiol group at the opposite end. PEG4-SPDP has a 4-unit polyethylene glycol spacer arm, which confers greater solubility to the crosslinker and linked proteins compared to crosslinkers having only hydrocarbon spacers. Pyridyldithiol reagents produce disulfide-containing linkages that can be cleaved with reducing agents such as dithiothreitol (DTT). Crosslinking experiments with SPDP reagents are not limited to those involving proteins. Any of a variety of molecules with primary amines and sulfhydryl groups can be modified or crosslinked using an SPDP reagent. |
| Features and Benefits【特点和优势】 |
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| Caution【注意】 | This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature. |
产品性质
| Quality Level【质量水平】 | 100 |
| mol wt【分子量】 | 559.65 |
| reaction suitability | reagent type: cross-linking reagent |
| storage condition【储存条件】 | desiccated |
| solubility【溶解性】 | water: soluble |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | O=C(CCSSC1=CC=CC=N1)NCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
