您的位置：首页 > 产品中心 > 1078166-57-0， PF-04418948
PF-04418948
产品别名
1078166-57-0
PF-04418948
1-(4-Fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]-3-azetidinecarboxylic acid
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H20FNO5 |
| Molecular weight | 409.41 |
| NACRES | NA.77 |
| Application【应用】 | PF-04418948 has been used in TG (trigeminal ganglion) explant culture. |
| Biochem/physiol Actions【生化/生理作用】 | PF-04418948 is a PGE2 Receptor (EP2) specific antagonist (IC50 = 16 nM) with greater than 2000-fold selectivity over other EP subtypes. PF-04418948 inhibits EP2 activity in smooth muscle preps from human, dog and mouse. PF-04418948 represses the formation of colorectal tumor. |
| Other Notes【其他说明】 | This compound was developed by Pfizer for Lipid Signaling research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
| Legal Information【法律信息】 | Sold for research purposes under agreement from Pfizer Inc. Pfizer is a registered trademark of Pfizer, Inc. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| manufacturer/tradename | Pfizer® |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 20 mg/mL, clear |
| originator【创始人】 | Pfizer |
| storage temp.【储存温度】 | room temp |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
