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PF-06284674
产品别名
1434288-24-0
PF-06284674
2-(1H-Benzimidazol-1-ylmethyl)-6-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H14N4O |
| Molecular weight | 290.32 |
| MDL number | MFCD29037211 |
| PubChem Substance ID【PubChem化学物质编号】 | 329823823 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | PF-06284674 is a cell permeable, potent and selective M2 isoform of pyruvate kinase (PKM2) activator. |
| Other Notes【其他说明】 | This compound was developed by Pfizer for Nitric Oxide & Cell Stress research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
| Legal Information【法律信息】 | Sold for research purposes under agreement from Pfizer Inc. Pfizer is a registered trademark of Pfizer, Inc. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| manufacturer/tradename | Pfizer® |
| color【颜色】 | white to brown |
| solubility【溶解性】 | DMSO: 10 mg/mL, clear |
| originator【创始人】 | Pfizer |
| storage temp.【储存温度】 | room temp |
| SMILES string | O=C1N2C(C=CC=C2C)=NC(CN(C=N3)C4=C3C=CC=C4)=C1 |
| InChI | 1S/C17H14N4O/c1-12-5-4-8-16-19-13(9-17(22)21(12)16)10-20-11-18-14-6-2-3-7-15(14)20/h2-9,11H,10H2,1H3 |
| InChI key | ICTBPKWPCGSFPZ-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P280 - P304 + P340 + P312 - P305 + P351 + P338 - P337 + P313 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
