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酚妥拉明

Phentolamine Mesylate
产品编号:3180997
规格:Pharmaceutical Secondary Standard; Certified Reference Material
CAS NO:65-28-1
包装规格:1 G
产品类别:进口试剂
品牌:Supelco
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
31809971 G1760
产品别名

65-28-1

酚妥拉明

Phentolamine Mesylate

2-(N-[m-Hydroxyphenyl]-p-toluidinomethyl)imidazoline

Phentolamine methanesulfonate salt

酚妥拉明 甲磺酸盐

2-(N-[m-羟基苯基]-p-甲苯氨基甲基)咪唑啉

结构式
基本信息
Linear Formula【线性分子式】
C17H19N3O · CH3SO3H
Molecular weight
377.46
EC number【EC 号】
200-604-6
MDL number
MFCD00134201
PubChem Substance ID【PubChem化学物质编号】
329823376
NACRES
NA.24
General description【一般描述】
Phentolamine Mesylate belongs to the class of alpha adrenergic antagonist drugs. It is used in the treatment of pheochromocytoma-related hypertension, erectile dysfunction and in the diagnosis of pheochromocytoma and norepinephrine-related dermal necrosis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application【应用】
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Phentolamine Mesylate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chemiluminescence technique.
Biochem/physiol Actions【生化/生理作用】
α-肾上腺素受体拮抗剂;外周血管舒张剂。
Analysis Note【分析说明】
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Other Notes【其他说明】
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote【附注】
To see an example of a Certificate of Analysis for this material enter LRAC3261 in the slot below. This is an example certificate only and may not be the lot that you receive.
产品性质
Quality Level【质量水平】
300
grade【等级】
certified reference material
pharmaceutical secondary standard
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
180-182 ℃ (lit.)
application(s)
pharmaceutical (small molecule)
format【格式】
neat
pharmacopeia traceability【药典可追溯性】
traceable to PhEur Y0001127
traceable to USP 1530004
storage temp.【储存温度】
2-30℃
SMILES string
CS(O)(=O)=O.Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3
InChI
1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;1-5(2,3)4/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H3,(H,2,3,4)
InChI key
OGIYDFVHFQEFKQ-UHFFFAOYSA-N
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H302 - H315 - H319 - H335
Precautionary Statements
P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
Hazard Classifications【危险分类】
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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