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Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)-block-decane
| 产品编号： | 3185069 |
| 规格： | PEG average Mn 2,000, PDLLA average Mn 2,000 |
| 包装规格： | 1 G |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Poly(ethylene glycol) methyl ether-block-poly(
PEG-PDLLA-decane
PEG-b-PLA-b-decane
PEG-PLA
结构式
基本信息
| NACRES | NA.23 |
| General description【一般描述】 | Block copolymer micelles are widely used in drug delivery applications. PEG-PDLLA is a biodegradable polymeric micelle which is used as a carrier for hydrophobic drugs like Paclitaxel. The hydrophilic PEG and hydrophobic PDLLA form the micelle core wherein the hydrophobic drug is loaded. The incorporation of the 10-alkyl end cap (decane) increases the hydrophobicity of the micelle core and increases its solubilizing capability for hydrophobic drugs.† |
| Application【应用】 | Used as a carrier for the controlled and targeted release of anticancer hydrophobic drugs. |
| Features and Benefits【特点和优势】 |
|
产品性质
| mol wt【分子量】 | PDLLA average Mn 2,000 PEG average Mn 2,000 average Mn 4,000 (total) |
| Quality Level【质量水平】 | 100 |
| degradation timeframe【降解时间线】 | 2-5 weeks |
| transition temp【转变温度】 | Tm 29-33 ℃ |
| PDI | <1.1 (typical PEG) <1.2 <1.3 (overall) |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 1 g in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Flash Point(F)【闪点(F)】 | 230.0 °F |
| Flash Point(C)【闪点(C)】 | > 110 ℃ |
