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Procarbazine hydrochloride
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3208186 | 10 MG | 1101 | |||
| 3208186 | 50 MG | 3860 |
产品别名
366-70-1
Procarbazine hydrochloride
N-(1-Methylethyl)-4-[(2-methylhydrazinyl)methyl]benzamide hydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C12H19N3O·HCl |
| Molecular weight | 257.76 |
| EC number【EC 号】 | 206-678-6 |
| MDL number | MFCD00072082 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825106 |
| NACRES | NA.77 |
| Application【应用】 | Procarbazine, an antineoplastic alkylating agent, may be used to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an anticancer agent. It may be used to study new combination of anticancer drugs. Procarbazine hydrochloride has been used to study its physicochemical property. |
| Biochem/physiol Actions【生化/生理作用】 | Procarbazine is an antineoplastic alkylating agent widely used in cancer chemotherapy in combination with other compounds. It has multiple mechanisms of action. Procarbazine inhibits protein, RNA and DNA synthesis in addition to being an alkylating agent. Procarbazine is metabolized to azoprocarbazine either by cytochrome P450 enzyme and monoamine oxidase in an NADPH (nicotinamide adenine diphosphate) dependent or independent manner. It is considered neurotoxic. Procarbazine is used in combination with therapy for treating Hodgkin′s disease. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to tan |
| solubility【溶解性】 | DMSO: ≥18 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cl.CNNCc1ccc(cc1)C(=O)NC(C)C |
| InChI | 1S/C12H19N3O.ClH/c1-9(2)15-12(16)11-6-4-10(5-7-11)8-14-13-3;/h4-7,9,13-14H,8H2,1-3H3,(H,15,16);1H |
| InChI key | DERJYEZSLHIUKF-UHFFFAOYSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07,GHS08 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H302 - H341 - H350 - H360 |
| Precautionary Statements | P201 - P301 + P312 + P330 - P308 + P313 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Repr. 1A |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
