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氯胍 盐酸盐
Proguanil hydrochloride
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3208237 | 10 MG | 1160 | |||
| 3208237 | 50 MG | 3350 |
产品别名
637-32-1
氯胍 盐酸盐
Proguanil hydrochloride
Chlorguanide
N1-(4-Chlorophenyl)-N5-isopropylbiguanide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H16ClN5·HCl |
| Molecular weight | 290.19 |
| EC number【EC 号】 | 211-283-7 |
| MDL number | MFCD01732193 |
| PubChem Substance ID【PubChem化学物质编号】 | 329799959 |
| NACRES | NA.77 |
| Application【应用】 | Proguanil (chlorguanide) may be used in anti-parasitic protozoan drug development to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an antimalarial drug. |
| Biochem/physiol Actions【生化/生理作用】 | Chlorguanide (proguanil) is combined with atovaquone for malaria prophylaxis. The two compounds act synergistically to inhibit the plasmodial dihydrofolate reductase (DHFR) and interrupt the electron transport chain. Mutations in DHFR account for the development of resistant strains. |
| Features and Benefits【特点和优势】 | This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | solid |
| storage condition【储存条件】 | desiccated |
| solubility【溶解性】 | acetonitrile: water: ~1 mg/mL (60/40) |
| originator【创始人】 | AstraZeneca |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cl.CC(C)NC(=N)NC(=N)Nc1ccc(Cl)cc1 |
| InChI | 1S/C11H16ClN5.ClH/c1-7(2)15-10(13)17-11(14)16-9-5-3-8(12)4-6-9;/h3-7H,1-2H3,(H5,13,14,15,16,17);1H |
| InChI key | SARMGXPVOFNNNG-UHFFFAOYSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
