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PRT4165
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| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3208854 | 5 MG | 1120 | |||
| 3208854 | 25 MG | 3940 |
产品别名
31083-55-3
PRT4165
2-(3-Pyridinylmethylene)-1H-indene-1,3(2H)-dione; 2-(3-Pyridylmethylene)-1,3-indandione
NSC 600157
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C15H9NO2 |
| Molecular weight | 235.24 |
| MDL number | MFCD00435709 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825631 |
| Biochem/physiol Actions【生化/生理作用】 | PRT4165 is a potent inhibitor of PRC1 (polycomb-repressive complex 1)-mediated histone H2A ubiquitylation in vivo and in vitro. PRT4165 inhibits the in vitro histone H2A E3 ubiquitin ligase activity of PRC1 components RING1, RNF2, and a BMI1/RNF2 complex. PRT4165 also inhibits DNA double-strand breaks induced ubiquitylation of histone H2AX. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 20 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C1C(C(C2=C1C=CC=C2)=O)=CC3=CN=CC=C3 |
| InChI | 1S/C15H9NO2/c17-14-11-5-1-2-6-12(11)15(18)13(14)8-10-4-3-7-16-9-10/h1-9H |
| InChI key | OMHZFEWYVFWVLI-UHFFFAOYSA-N |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
