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Rabbit anti-BRCA1 Antibody, Affinity Purified
产品别名
Rabbit anti-BRCA1 Antibody, Affinity Purified
complementation group S
regulatory subunit 53
truncated breast cancer type 1 susceptibility protein
breast cancer 1
early onset
truncated BRCA1
breast and ovarian cancer sususceptibility protein 1
BRCC1
RING finger protein 53
truncated breast and ovarian cancer sususceptibility protein 1
Fanconi anemia
RNF53
early onset breast cancer 1
truncated breast and ovarian cancer susceptibility protein 1
FANCS
PNCA4
protein phosphatase 1
BRCAI
BRCA1/BRCA2-containing complex
PSCP
breast and ovarian cancer susceptibility protein 1
IRIS
BROVCA1
subunit 1
PPP1R53
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | The epitope recognized by PLA0185 maps to a region between residue 250 and 300 of human breast cancer 1 using the numbering given in entry NP_009225.1 (GeneID 672). |
| Physical form【外形】 | Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide |
| Other Notes【其他说明】 | BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| grade【等级】 | Powered by Bethyl Laboratories, Inc. |
| species reactivity | human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | immunohistochemistry: 1:500- 1:2,000 immunoprecipitation (IP): 2-10 μg/mg western blot: 1:500- 1:2,500 |
| accession no.【登记号】 | NP_009225.1 |
| UniProt accession no.【UniProt登记号】 | P38398 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | rabbit ... BRCA1(672) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
