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Rabbit anti-MDC1 Antibody, Affinity Purified
产品别名
Rabbit anti-MDC1 Antibody, Affinity Purified
NFBD1
KIAA0170
Em:AB023051.5
homologue to Drosophila photoreceptor protein calphotin
Nuclear factor with BRCT domains 1
mediator of DNA-damage checkpoint 1
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | The epitope recognized by PLA0016 maps to a region between residues 475 and 525 of human Mediator of DNA Damage Checkpoint 1 using the numbering given in entry NP_055456.1 (GeneID 9656). |
| Physical form【外形】 | Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide |
| Other Notes【其他说明】 | MDC1 is required for the S- and G2/M-checkpoint-mediated cell cycle arrest in response to DNA damage. MDC1 interacts with H2AX near sites of DNA double-strand breaks and recruits ATM kinase to foci of DNA damage. MDC1 also appears to regulate the function of other proteins involved in the DNA damage checkpoint such as BRCA1 and Chk2. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| grade【等级】 | Powered by Bethyl Laboratories, Inc. |
| species reactivity | human |
| technique(s) | immunoprecipitation (IP): 2-5 μg/mg western blot: 1:2000-1:10000 |
| accession no.【登记号】 | NP_055456.1 |
| UniProt accession no.【UniProt登记号】 | Q14676 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | rabbit ... MDC1(9656) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
