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Rabbit anti-mTOR Antibody, Affinity Purified
产品别名
Rabbit anti-mTOR Antibody, Affinity Purified
FK506 binding protein 12-rapamycin associated protein 1
mtor
RAPT1
SKS
FLJ44809
FRAP
Mechanistic target of rapamycin
Mammalian target of rapamycin
rapamycin associated protein FRAP2
FRAP2
mechanistic target of rapamycin (serine/threonine kinase)
FK506 binding protein 12-rapamycin associated protein 2
FK506-binding protein 12-rapamycin complex-associated protein 1
FRAP1
Rapamycin target protein
FKBP-rapamycin associated protein
Rapamycin target protein 1
FKBP12-rapamycin complex-associated protein
Rapamycin and FKBP12 target 1
RAFT1
FKBP12-rapamycin complex-associated protein 1
dJ576K7.1 (FK506 binding protein 12-rapamycin associated protein 1)
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | The epitope recognized by PLA0114 maps to a region between residue 200 and 250 of human Mammalian Target of Rapamycin using the numbering given in entry NP_004949.1 (GeneID 2475). |
| Physical form【外形】 | Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide |
| Other Notes【其他说明】 | Studies of the mammalian target of rapamycin (mTOR) and its homologs demonstrate a role in integrating signals from growth factors, nutrients, stress, and cellular energy levels to control cell growth, translation initiation, ribosome biogenesis, and transcription factor localization. mTOR is the direct target of the cell cycle arresting activity of rapamycin. mTOR interacts with Raptor or Rictor to form the mTORC1 and mTORC2 complexes respectively. The mTORC1 complex also includes mLst8/GbetaL and functions to phosphorylate S6K and 4EBP1. The mTORC2 complex also includes mLst8/GbetaL, mSIN1 and protor-1 and functions to phosphorylate Akt. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| grade【等级】 | Powered by Bethyl Laboratories, Inc. |
| species reactivity | human |
| technique(s) | immunoprecipitation (IP): 2-10 μg/mg proximity ligation assay: suitable western blot: 1:2,000-1:10,000 |
| accession no.【登记号】 | NP_004949.1 |
| UniProt accession no.【UniProt登记号】 | P42345 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | rabbit ... mTOR(2475) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
