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Rabbit anti-NBS1 Antibody, Affinity Purified
产品别名
Rabbit anti-NBS1 Antibody, Affinity Purified
AT-V1
p95 protein of the MRE11/RAD50 complex
Nijmegen breakage syndrome 1 (nibrin)
ATV
NBS1
Nijmegen breakage syndrome protein 1
Cell cycle regulatory protein p95
AT-V2
NBS
P95
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | The epitope recognized by PLA0179 maps to a region between residue 704 and 754 of human Nibrin using the numbering given in entry NP_002476.2 (GeneID 4683). |
| Physical form【外形】 | Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide |
| Other Notes【其他说明】 | Mutations in NBS1 (Nijmegen Breakage Syndrome 1), also known as nibrin, are associated with the autosomal recessive syndrome, Nijmegen breakage syndrome, characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. At the cellular level, NBS1 is part of the MRE11/RAD50 double-strand break repair complex that is critical to the DNA damage response, DNA recombination, telomere integrity, and cell cycle checkpoint control. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| grade【等级】 | Powered by Bethyl Laboratories, Inc. |
| species reactivity | human |
| technique(s) | immunohistochemistry: 1:100- 1:500 immunoprecipitation (IP): 2- 5 μg/mg western blot: 1:2,000- 1:10,000 |
| accession no.【登记号】 | NP_002476.2 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | rabbit ... NBS1(4683) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
