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Rabbit anti-Phospho Chk1 (S317) Antibody, Affinity Purified
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | Immunogen for PLA0056 was a phosphorylated synthetic peptide, which represented a portion of human Checkpoint Kinase 1 (GeneID 1111) around serine 317 according to the numbering given in entry NP_001265.1. |
| Physical form【外形】 | Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide |
| Other Notes【其他说明】 | Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| grade【等级】 | Powered by Bethyl Laboratories, Inc. |
| species reactivity | human, horse, rabbit, rhesus monkey, dog, gorilla, chimpanzee, pig, primate |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | western blot: 1:500- 1:5,000 |
| accession no.【登记号】 | NP_001265.1 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | human ... CHEK1(1111) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
