Rabbit anti-PIM1 Antibody, Affinity Purified

NA.41

The epitope recognized by PLA0088 maps to a region between residue 250 and the C-terminus (residue 313) of human PIM1 oncoprotein using the numbering given in Swiss-Prot entry P11309 (GeneID 5292).

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

PIM1 is a member of the PIM family of proto-oncogenes that functions as a distinct class of serine/threonine protein kinases involved in growth factor signaling. PIM1 was originally identified as a target of proviral activation in T-cell lymphomas induced by Moloney murine leukemia virus. PIM1 appears to play a role in many aspects of cell growth, proliferation, and apoptosis. PIM1 is required for efficient cell cycle induction of peripheral T-cells in response to IL-2 signaling. PIM1 substrates include p21 cip1/waf1, CDC25A, PTP-U2, NuMA, and PAP-1.

rabbit

100

affinity purified immunoglobulin

primary antibodies

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human

immunoprecipitation (IP): 4-8 μg/mg
western blot: 1:3,000- 1:15,000

P11309

P11309

wet ice

2-8℃

rabbit ... PIM1(5292)

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12 - Non Combustible Liquids

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