Rabbit anti-Rad9 Antibody, Affinity Purified

NA.41

The epitope recognized by PLA0151 maps to a region between residue 350 and the C-terminus (residue 391) of human Rad9 using the numbering given in entry NP_004575.1 (GeneID 5883).

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Rad9 is a cell-cycle checkpoint protein with 3′-5′ exonuclease activity and is part of the 9-1-1 complex. The 9-1-1 complex, also called the checkpoint clamp, is a trimeric complex that includes Rad9, Hus1, and Rad1. This complex is recruited by the RAD17/RFC clamp loader to DNA lesions where it aids in the activation of Chk2 by ATM and ATRIP and the subsequent triggering of the checkpoint signaling cascade. In addition to its role in sensing DNA damage, Rad9 also functions in the base excision repair process of DNA repair.

rabbit

100

affinity purified immunoglobulin

primary antibodies

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human

immunohistochemistry: 1:500-1:2,000
immunoprecipitation (IP): 2- 5 μg/mg
western blot: 1:2,000- 1:10,000

NP_004575.1

wet ice

2-8℃

rabbit ... Rad9(5883)

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12 - Non Combustible Liquids

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