Rabbit anti-SETDB1 Antibody, Affinity Purified

NA.41

The epitope recognized by PLA0036 maps to a region between residues 1125 and 1175 of human SET Domain, Bifurcated 1 using the numbering given in entry NP_036564.2 (GeneID 9869).

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

SETDB1 (SET domain, bifurcated 1) is a member of the SET (SuVar3-9, enhancer of Zeste, Trithorax) domain-containing protein family that functions as a histone and DNA methyltransferase. SETDB1 was identified through its interaction with ERG (ets-related gene) and KAP1 (KRAB-associated protein1) and was later demonstrated to interact with HDAC1/2 (histone deacetylase 1/2), DNA methyltransferase 3s (DNMT3s), mSin3A/3B, HP1, and MBD1. SETDB1 is suggested to play a role in transcriptional repression important to early development.

rabbit

100

affinity purified immunoglobulin

primary antibodies

Powered by Bethyl Laboratories, Inc.

human

western blot: 1:500-1:2,500

NP_036564.2

Q15047

wet ice

2-8℃

rabbit ... SETDB1(9869)

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12 - Non Combustible Liquids

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