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Rabbit anti-STUB1/CHIP Antibody, Affinity Purified
产品别名
Rabbit anti-STUB1/CHIP Antibody, Affinity Purified
SDCCAG7
Antigen NY-CO-7
heat shock protein A binding protein 2 (c-terminal)
SCAR16
E3 ubiquitin protein ligase
serologically defined colon cancer antigen 7
CLL-associated antigen KW-8
STIP1 homology and U box-containing protein 1
UBOX1
STIP1 homology and U-box containing protein 1
CHIP
Carboxy terminus of Hsp70-interacting protein
NY-CO-7
HSPABP2
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | The epitope recognized by PLA0196 maps to a region between residue 1 and 50 of human STIP1 homology and U-box containing protein 1 (carboxy terminus of Hsp70-interacting protein) using the numbering given in entry NP_005852.2 (GeneID 10273). |
| Physical form【外形】 | Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide |
| Other Notes【其他说明】 | STUB1/CHIP is an E3 ubiquitin ligase and co-chaperone of heat-shock protein 70 (Hsp70). STUB1/CHIP interacts with Hsp70 to monitor protein folding and direct misfolded proteins for proteasomal degradation. It has been found to also associate with Hsp90 to remove phosphorylated protein tau, a protein that accumulates in the brains of Alzheimer′s and Down′s syndrome patients. STUB1/CHIP has been reported to also have intrinsic chaperone activity and recognize non-native proteins in response to heat stress. In this way, STUB1/CHIP has been shown to be a direct chaperone for p53. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| grade【等级】 | Powered by Bethyl Laboratories, Inc. |
| species reactivity | mouse, human |
| technique(s) | immunoprecipitation (IP): 2-5 μg/mg western blot: 1:2,000- 1:10,000 |
| accession no.【登记号】 | NP_005852.2 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | rabbit ... STUB1/CHIP(10273) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
