Rabbit anti-TIF1 Alpha/TRIM24 Antibody, Affinity Purified

NA.41

The epitope recognized by PLA0147 maps to a region between residue 700 and 750 of human Transcriptional Intermediary Factor 1 Alpha (Tripartite Motif-Containing 24 ) using the numbering given in entry NP_056989.2 (GeneID 8805).

Tris-buffered Saline containing 0.1% BSA with 0.09% Sodium Azide

TIF1 Alpha/TRIM24 is a member of a family of proteins that control transcription and chromatin remodeling through their interaction with transcription factors. The family of TIF1s (transcriptional intermediary factor 1) includes TIF1-alpha, TIF1-beta, and TIF1-gamma. TIF1-alpha plays an important role in development and mediates transcriptional control by interacting with the AF2 region of nuclear receptors such as estrogen, retinoic acid, and vitamin D3 receptors. TIF1-alpha has been shown to be a repressor of transcription. This transcriptional repression involves histone deacetylation and interaction with members of the heterochromatin protein 1 family.

rabbit

100

affinity purified immunoglobulin

primary antibodies

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mouse, human

ChIP: 4-30 μg
immunohistochemistry: 1:200- 1:1,000
immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000- 1:10,000

NP_056989.2

wet ice

2-8℃

human ... TRIM24(8805)

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12 - Non Combustible Liquids

WGK 1