Rabbit anti-TLK1 Antibody, Affinity Purified

NA.41

The epitope recognized by PLA0176 maps to a region between residue 150 and 200 of human tousled-like kinase 1 using the numbering given in entry NP_036422.3 (GeneID 9874).

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Tousled-like kinase 1 (TLK1) is a serine/threonine kinase involved in chromatin assembly and the DNA damage response. The tousled (Tsl) kinase was first identified in Arabidopsis thaliana and speculated to be involved in cell division during patterning of plant organs. There are two tousled-like kinases in humans, TLK1 and TLK2, that can dimerize or heterodimerize for function and can be phosphorylated and inactivated by Chk1 in response to DNA damage. The histone chaperone, Asf1 (anti-silencing function 1), has been reported as a substrate for both TLK1 and TLK2. TLK1 has also been shown to be important for cell cycle progression and proper chromosome segregation.

rabbit

100

affinity purified immunoglobulin

primary antibodies

Powered by Bethyl Laboratories, Inc.

mouse, human

immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

NP_036422.3

Q9UKI8

wet ice

2-8℃

rabbit ... TLK1(9874)

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12 - Non Combustible Liquids

WGK 1