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Rc-Ome
产品别名
Rc-Ome
trans-6,4′-dimethoxyretrochalcone
(2E)-3-(2-hydroxy-5-methoxyphenyl)-1-(4-methoxyphenyl)-2-Propen-1-one
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H16O4 |
| Molecular weight | 284.31 |
| NACRES | NA.77 |
| Application【应用】 | Rc-Ome may be used in GABAA-mediated cell signaling studies. |
| Biochem/physiol Actions【生化/生理作用】 | Rc-OMe is a GABAA PAM that distinguishes α1β2γ2s from α1β2 receptors. The compound has very weak potentiating effects on α1β2, but potentiates GABA-elicited currents of α(123)β2γ2s receptors, all with low μM EC50s. Rc-OMe acts at a binding site that is distinct from BDZ, pentobarbital and loreclezole modulatory sites. |
| Features and Benefits【特点和优势】 | This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | , light to dark yellow |
| solubility【溶解性】 | DMSO: ≥10 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS09 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H400 |
| Precautionary Statements | P273 |
| Hazard Classifications【危险分类】 | Aquatic Acute 1 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
