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Rebamipide hydrate

产品编号:3214623
规格:≥98% (HPLC), powder
CAS NO:90098-04-7
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
32146235 MG1115
321462325 MG3090
产品别名

90098-04-7

Rebamipide hydrate

OPC 12759 hydrate

Mucosta hydrate

α-[(4-Chlorobenzoyl)amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid hydrate

Proamipide hydrate

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C19H15ClN2O4 · xH2O
Molecular weight
370.79 (anhydrous basis)
MDL number
MFCD11114396
PubChem Substance ID【PubChem化学物质编号】
329824033
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
Rebamipide is an anti-ulcer agent with free-radical scavenging and anti-inflammatory effects. It has been used for mucosal protection, healing of gastroduodenal ulcers, and treatment of gastritis. It works by enhancing mucosal defense, scavenging free radicals, and temporarily activating COX-2 genes. Rebamipide significantly reduced ulcerogenesis and maintained mucosal superoxide dismutase (SOD) activity. It has also been used for the treatment of Behçet′s disease. Rebamipide may be involved in a noval mechanism to enhance tear secretion and increase mucin levels covering conjunctiva and cornea.
Rebamipide helps to reduce intestinal injury, stimulated by radiation.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white
solubility【溶解性】
DMSO: >5 mg/mL
SMILES string
O.OC(=O)C(CC1=CC(=O)Nc2ccccc12)NC(=O)c3ccc(Cl)cc3
InChI
1S/C19H15ClN2O4.H2O/c20-13-7-5-11(6-8-13)18(24)22-16(19(25)26)9-12-10-17(23)21-15-4-2-1-3-14(12)15;/h1-8,10,16H,9H2,(H,21,23)(H,22,24)(H,25,26);1H2
InChI key
WQRHVBKNEDPECA-UHFFFAOYSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Pictograms【象形图】
GHS06
Signal word【警示用语:】
Danger
Hazard Statements
H301
Precautionary Statements
P301 + P310
Hazard Classifications【危险分类】
Acute Tox. 3 Oral
Storage Class Code【储存分类代码】
6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Faceshields, Gloves, type N95 (US)
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