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Reversan
产品别名
313397-13-6
Reversan
CBLC4H10
N-[3-(4-Morpholinyl)propyl]-5,7-diphenyl-pyrazolo[1,5-a]pyrimidine-3-carboxamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C26H27N5O2 |
| Molecular weight | 441.52 |
| MDL number | MFCD01528184 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825203 |
| NACRES | NA.77 |
| Application【应用】 | Reversan may be used in cell signaling studies. |
| Biochem/physiol Actions【生化/生理作用】 | Reversan increases the efficacy of vincristine and etoposide and increases the sensitivity of murine models of neuroblastoma to conventional chemotherapy. Reversan is a selective and nontoxic multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (P-gp) inhibitor. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | faintly yellow to yellow |
| solubility【溶解性】 | DMSO: ≥8 mg/mL at ~60 ℃ |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C(NCCCN1CCOCC1)c2cnn3c(cc(nc23)-c4ccccc4)-c5ccccc5 |
| InChI | 1S/C26H27N5O2/c32-26(27-12-7-13-30-14-16-33-17-15-30)22-19-28-31-24(21-10-5-2-6-11-21)18-23(29-25(22)31)20-8-3-1-4-9-20/h1-6,8-11,18-19H,7,12-17H2,(H,27,32) |
| InChI key | JTRXWCLQFAZHGP-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
