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S15535
产品别名
146998-34-7
S15535
1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-4-(2,3-dihydro-1h-inden-2-yl)-piperazine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H24N2O2 |
| Molecular weight | 336.43 |
| MDL number | MFCD00911672 |
| PubChem Substance ID【PubChem化学物质编号】 | 329824452 |
| NACRES | NA.77 |
| Application【应用】 | S15535 has been used as a serotonin 1A receptor (5-HT1A) agonist in zebrafish. S15535 may be used in histamine 5-HT1A-medaited cell signaling studies. |
| Biochem/physiol Actions【生化/生理作用】 | S15535, a benzodioxane, is a selective but partial agonist of histamine serotonin 1A (5-HT1A) receptor. It activates presynaptic 5-HT1A receptors and suppresses the release of hippocampal 5-HT. It acts as an anxiolytic agent and modulates the cholinergic and cognitive function in rodents. Potent, orally active, partial 5-HT1A receptor agonist |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: ~6 mg/mL H2O: insoluble |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | C1COc2c(O1)cccc2N3CCN(CC3)C4Cc5ccccc5C4 |
| InChI | 1S/C21H24N2O2/c1-2-5-17-15-18(14-16(17)4-1)22-8-10-23(11-9-22)19-6-3-7-20-21(19)25-13-12-24-20/h1-7,18H,8-15H2 |
| InChI key | QJPPEMXOOWNICQ-UHFFFAOYSA-N |
| packaging【包装】 | 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS09 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H400 |
| Precautionary Statements | P273 |
| Hazard Classifications【危险分类】 | Aquatic Acute 1 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves |
