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产品别名
7370-21-0
SIB 1893
[E]-2-Methyl-6-[2-phenylethenyl]pyridine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C14H13N |
| Molecular weight | 195.26 |
| MDL number | MFCD02262120 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278718 |
| NACRES | NA.77 |
| Application【应用】 | SIB 1893 may be used in mGluR5 metabotropic glutamate receptor-mediated cell signaling studies. |
| Biochem/physiol Actions【生化/生理作用】 | SIB 1893 non-competitively inhibits glutamate-induced increase in Ca2+ at human metabotropic glutamate receptor 1 (hmGluR1).1 It also acts as a positive allosteric modulator of hmGluR4.2 Selective and noncompetitive mGlu5 metabotropic glutamate receptor antagonist. |
| Features and Benefits【特点和优势】 | This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | >99% |
| form【形式】 | solid |
| solubility【溶解性】 | DMSO: 18 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cc1cccc(\C=C\c2ccccc2)n1 |
| InChI | 1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+ |
| InChI key | SISOFUCTXZKSOQ-ZHACJKMWSA-N |
| Gene Information | human ... GRM1(2911), GRM5(2915) |
| packaging【包装】 | 10 mg in ampule |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
