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SR 57227A
产品别名
77145-61-0
SR 57227A
4-amino-1-(6-chloro-2-pyridyl)-piperidine hydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C10H14ClN3 · HCl |
| Molecular weight | 248.15 |
| MDL number | MFCD01756430 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278109 |
| NACRES | NA.77 |
| Application【应用】 | SR 57227A may be used in 5-HT3-mediated cell signaling studies. |
| Biochem/physiol Actions【生化/生理作用】 | SR 57227A is a highly selective of central and peripheral 5-HT3 receptors and an inhibitor of NMDA receptor-mediated responses in rat cortical pyramidal cells. It exhibits anti-depressant like effects in rats and decreased isolation-induced aggressive behavior. Potent and selective 5-HT3 serotonin receptor agonist. |
产品性质
| Quality Level【质量水平】 | 100 |
| form【形式】 | solid |
| color【颜色】 | white |
| solubility【溶解性】 | H2O: soluble 9 mg/mL |
| SMILES string | Cl.NC1CCN(CC1)c2cccc(Cl)n2 |
| InChI | 1S/C10H14ClN3.ClH/c11-9-2-1-3-10(13-9)14-6-4-8(12)5-7-14;/h1-3,8H,4-7,12H2;1H |
| InChI key | FUMINTAAUJUVMP-UHFFFAOYSA-N |
| Gene Information | human ... HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242) |
| packaging【包装】 | 5 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 - H315 - H319 - H335 |
| Precautionary Statements | P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
