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SU5614
产品别名
1055412-47-9
SU5614
(3Z)-5-Chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C15H13ClN2O |
Molecular weight | 272.73 |
MDL number | MFCD08443928 |
PubChem Substance ID【PubChem化学物质编号】 | 329823735 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | SU5614 is a FMS-like tyrosine kinase 3 (FLT3) inhibitor; selective inhibitor of VEGF and PDGF receptor tyrosine kinases. |
Features and Benefits【特点和优势】 | This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
Other Notes【其他说明】 | This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
Legal Information【法律信息】 | Sold for research purposes under agreement from Pfizer Inc. Pfizer is a registered trademark of Pfizer, Inc. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
manufacturer/tradename | Pfizer® |
color【颜色】 | orange |
solubility【溶解性】 | DMSO: ≥20 mg/mL |
originator【创始人】 | Pfizer |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | Cc1cc(C)c(\C=C2/C(=O)Nc3ccc(Cl)cc23)[nH]1 |
InChI | 1S/C15H13ClN2O/c1-8-5-9(2)17-14(8)7-12-11-6-10(16)3-4-13(11)18-15(12)19/h3-7,17H,1-2H3,(H,18,19)/b12-7- |
InChI key | XLBQNZICMYZIQT-GHXNOFRVSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Hazard Statements | H413 |
Hazard Classifications【危险分类】 | Aquatic Chronic 4 |
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |